ivive.app
hepatic clearance from in-vitro data, with an honest error bar
ivive.app
hepatic clearance from in-vitro data, with an honest error bar
ivive.app
Free IVIVE calculator: in-vitro CLint, fu,mic and fu,p to hepatic and plasma clearance, with the observed-clearance range from 301 reference drugs, a structure-only second opinion, lab correction, species scaling and an MCP server for LLMs.
Enter CLint, fu,mic and fu,p, or just a SMILES, and get hepatic and plasma clearance by well-stirred or parallel-tube IVIVE, together with how far off a prediction like this has been for real drugs. CLint 177.8 µL/min/mg · fu,mic 0.88 · fu,p 0.05 · Rb 0.53 CLint 135.6 µL/min/mg · fu,mic 0.43 · fu,p 0.10 · Rb 0.77
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Frequently asked questions
What is ivive.app?
ivive.app is hepatic clearance from in-vitro data, with an honest error bar. Free IVIVE calculator: in-vitro CLint, fu,mic and fu,p to hepatic and plasma clearance, with the observed-clearance range from 301 reference drugs, a structure-only second opinion, lab correction, species scaling and an MCP server for LLMs.
Is ivive.app free?
ivive.app has a free tier, with paid plans unlocking more.
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